NDP

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NDP Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NDP data layer compared with 22 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NDP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NDP expression acts as an unfavorable survival marker.

COAD and SARC are the cancer types where NDP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSMedianAll0.0010.871<.00124view →
SARCOSMedianAll0.1430.745<.0016view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NDP–COAD (OS)

Kaplan–Meier survival curve for NDP mutant vs wild-type samples in COAD.

Open the COAD breakdown →

Exploration