NDN

Across TCGA patient cohorts, NDN protein abundance is significantly associated with the RNA expression of many other genes, with 5,907 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NDN-associated genes across cancer lineages are FGF7, FILIP1L, and RCAN2. Each is linked with NDN in more than 4 cancer types. Because this analysis shows association rather than direction, both NDN-to-partner and partner-to-NDN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDN versus FGF7 in OV, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDN→partner) and Y-score (partner→NDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FGF7 →	+2.198	+0.870	<.001	.009	3	5
BRCA	FILIP1L →	+1.254	+0.682	<.001	.001	3	5
GBM	RCAN2 →	+1.490	+0.694	.001	.001	3	5
OV	MRGPRF →	+1.265	+1.544	<.001	<.001	3	5
OV	COL15A1 →	+1.459	+1.120	<.001	<.001	3	5
OV	CYS1 →	+1.584	+0.899	.002	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,907 associations by consensus.

NDN vs FGF7 — OV

Explore this scatter interactively →