NDN

Across TCGA cell cohorts, NDN RNA expression is significantly associated with the go_rna of many other GO terms, with 1,960 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NDN-associated GO terms across cancer lineages are Nucleic acid catabolic process, Purine nucleoside triphosphate metabolic process, and Purine ribonucleoside triphosphate metabolic process. Each is linked with NDN in more than 7 cancer types. Because this analysis shows association rather than direction, both NDN-to-partner and partner-to-NDN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleic acid catabolic process grouped by NDN-low versus NDN-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDN→partner) and Y-score (partner→NDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Nucleic acid catabolic process →	+0.048	+1.956	<.001	.004	3	7
SKIN	Purine nucleoside triphosphate metabolic process →	+0.048	+1.909	.002	.002	3	7
BREAST	Purine ribonucleoside triphosphate metabolic process →	+0.047	+0.852	<.001	.006	3	7
BLOOD_Myeloma	Protein exit from endoplasmic reticulum →	+0.126	+2.845	.001	.002	3	7
BLOOD_Myeloma	Endosomal lumen acidification →	+0.128	+2.878	<.001	.002	3	7
OVARY	Positive regulation of telomerase RNA localization to Cajal body →	+0.045	+1.562	.004	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,960 associations by consensus.

Nucleic acid catabolic process by NDN expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →