NDFIP2-AS1

Across TCGA pan-cancer cohorts, NDFIP2-AS1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated NDFIP2-AS1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher NDFIP2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NDFIP2-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and KIRP show a favorable association.

SKCM, LIHC, and HNSC are the cancer types where NDFIP2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.455	0.769	.009	36	view →
LIHC	OS	Tertile	III,IV	0.384	0.657	.011	36	view →
HNSC	DFS	Tertile	IV	0.405	0.633	.008	29	view →
MESO	DFS	Tertile	All	0.366	0.212	.017	28	view →
ESCA	OS	Quartile	All	0.336	0.519	.021	24	view →
KIRP	OS	Tertile	All	0.959	0.865	.031	18	view →
THYM	OS	Tertile	II,III,IV	0.794	0.976	.036	9	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	9	view →
DLBC	OS	Tertile	All	0.613	0.945	.049	9	view →
THCA	OS	Tertile	IV	0.790	1.000	.016	3	view →
STAD	DFS	Tertile	All	0.572	0.738	.048	3	view →
CESC	DFS	Quartile	All	0.398	0.586	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

NDFIP2-AS1–SKCM (DFS)

Open the SKCM breakdown →