NDEL1

Across TCGA cell cohorts, NDEL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,150 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NDEL1-associated GO terms across cancer lineages are Mitotic centrosome separation, Endosomal transport, and Cytosolic transport. Each is linked with NDEL1 in more than 16 cancer types. Because this analysis shows association rather than direction, both NDEL1-to-partner and partner-to-NDEL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic centrosome separation grouped by NDEL1-low versus NDEL1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDEL1→partner) and Y-score (partner→NDEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Mitotic centrosome separation →	+0.144	+0.904	<.001	<.001	3	17
STOMACH	Endosomal transport →	+0.064	+0.747	.001	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.075	+1.016	<.001	<.001	3	15
BREAST	Retrograde transport, endosome to Golgi →	+0.075	+0.976	<.001	.002	3	14
STOMACH	Vesicle-mediated transport to the plasma membrane →	+0.064	+0.633	<.001	.005	2	14
STOMACH	Golgi vesicle transport →	+0.067	+0.800	.003	.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,150 associations by consensus.

Mitotic centrosome separation by NDEL1 expression — BREAST

Explore this box plot interactively →