NDC1

Across TCGA patient cohorts, NDC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,326 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NDC1-associated proteins across cancer lineages are SMC2, SMC4, and HAT1. Each is linked with NDC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both NDC1-to-partner and partner-to-NDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDC1 versus SMC2 in UCEC, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NDC1→partner) and Y-score (partner→NDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SMC2 →	+0.731	+0.804	<.001	<.001	3	10
UCEC	SMC4 →	+0.650	+0.759	<.001	<.001	3	10
UCEC	HAT1 →	+0.407	+0.650	<.001	<.001	3	10
BRCA	POLD1 →	+0.394	+0.673	<.001	<.001	3	10
OV	PTPN2_S304 →	+0.886	+0.778	<.001	<.001	3	9
OV	PURA →	-0.422	-0.520	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,326 associations by consensus.

NDC1 vs SMC2 — UCEC

Explore this scatter interactively →