NCR3LG1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NCR3LG1 mutation is significantly associated with the RNA expression of many other genes, with 540 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCR3LG1-associated genes across cancer lineages are DGKE, FAM122C, and NTAN1. Each is linked with NCR3LG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCR3LG1-to-partner and partner-to-NCR3LG1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCR3LG1→partner) and Y-score (partner→NCR3LG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECDGKE →+0.638+3.233.002.00931
UCECFAM122C →+0.468+3.470.001.00331
UCECNTAN1 →+0.812+3.513<.001.00231
UCECABHD3 →+0.806+3.470.002.00331
UCECGRIN2C →+0.538+3.379<.001.00731
UCECSSTR5 →+0.546+4.035.006<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 540 associations by consensus.

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