Across TCGA patient cohorts, NCR3LG1 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCR3LG1-associated genes across cancer lineages are Mre11, STAT3_pY705, and Tuberin. Each is linked with NCR3LG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCR3LG1-to-partner and partner-to-NCR3LG1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCR3LG1→partner) and Y-score (partner→NCR3LG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mre11 →	-0.116	-3.169	.014	.020	3	1
UCEC	STAT3_pY705 →	-0.524	-3.169	<.001	.020	3	1
UCEC	Tuberin →	+0.393	+2.817	.007	.036	3	1
UCEC	Caspase-8 →	-0.337	-3.169	.014	.020	2	1
UCEC	MEK1 →	+0.487	+3.169	.015	.020	1	1
UCEC	Shc_pY317 →	-0.260	-3.169	.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

NCR3LG1 survival (RNA) · tumor vs normal (RNA) · all NCR3LG1 data types