NCOR1

Across TCGA cell cohorts, NCOR1 mutation is significantly associated with the RNA expression of many other genes, with 1,631 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NCOR1-associated genes across cancer lineages are MEX3C, TMA16, and MT-CO3. Each is linked with NCOR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NCOR1-to-partner and partner-to-NCOR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEX3C grouped by NCOR1-low versus NCOR1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOR1→partner) and Y-score (partner→NCOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MEX3C →	+0.758	+2.222	<.001	.001	3	3
LARGE_INTESTINE	TMA16 →	+0.523	+3.459	<.001	<.001	3	3
LARGE_INTESTINE	MT-CO3 →	-0.716	-3.459	<.001	<.001	3	3
BLOOD_Leukemia	USP34 →	+0.364	+1.896	.007	.008	3	3
SKIN	CHRND →	+0.038	+2.353	.007	.008	3	2
SKIN	EEF1A1 →	+0.509	+3.212	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,631 associations by consensus.

MEX3C by NCOR1 expression — LARGE_INTESTINE

Explore this box plot interactively →