NCOR1

Across TCGA pan-cancer cohorts, NCOR1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated NCOR1 data layer compared with 8 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher NCOR1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated NCOR1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

KIRC, BLCA, and HNSC are the cancer types where NCOR1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.728	0.526	<.001	113	view →
BLCA	DFS	Median	All	0.449	0.564	.003	49	view →
HNSC	DFS	Median	All	0.426	0.249	<.001	42	view →
BRCA	DFS	Tertile	III,IV	0.881	0.712	.001	33	view →
ACC	DFS	Tertile	All	0.124	0.635	.001	31	view →
MESO	DFS	Quartile	III,IV	0.214	0.595	<.001	30	view →
KICH	DFS	Median	III,IV	0.318	0.901	.004	24	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
LUSC	DFS	Tertile	All	0.287	0.476	.008	24	view →
UVM	DFS	Quartile	II,III,IV	0.306	0.741	.009	18	view →
READ	OS	Quartile	II,III,IV	0.889	0.339	.001	17	view →
THYM	DFS	Median	III,IV	1.000	0.402	.004	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

NCOR1–KIRC (DFS)

Open the KIRC breakdown →