NCOA7

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NCOA7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,778 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NCOA7-associated GO terms across cancer lineages are Response to manganese ion, Regulation of neuron apoptotic process, and Type II interferon-mediated signaling pathway. Each is linked with NCOA7 in more than 11 cancer types. Because this analysis shows association rather than direction, both NCOA7-to-partner and partner-to-NCOA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to manganese ion grouped by NCOA7-low versus NCOA7-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA7→partner) and Y-score (partner→NCOA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTResponse to manganese ion →+0.133+1.888<.001<.001312
OVARYRegulation of neuron apoptotic process →+0.088+1.354<.001<.001311
LUNG_NSCLC_LUSCType II interferon-mediated signaling pathway →+0.237+1.640<.001<.001310
LIVERCanonical NF-kappaB signal transduction →+0.076+1.124.003.001211
BREASTProteasomal ubiquitin-independent protein catabolic process →+0.106+2.049<.001<.001310
URINARY_TRACTRegulation of response to endoplasmic reticulum stress →+0.062+1.462.007.004310
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,778 associations by consensus.

Response to manganese ion by NCOA7 expression — BREAST

Box plot of Response to manganese ion in NCOA7-low vs NCOA7-high samples in BREAST.

Explore this box plot interactively →

Exploration