Across TCGA cell cohorts, NCOA6 mutation is significantly associated with the RNA expression of many other genes, with 512 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCOA6-associated genes across cancer lineages are WASF1, OR2AG1, and ARHGEF10. Each is linked with NCOA6 in more than 3 cancer types. Because this analysis shows association rather than direction, both NCOA6-to-partner and partner-to-NCOA6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA6→partner) and Y-score (partner→NCOA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	WASF1 →	+0.799	+3.743	.004	<.001	3	3
BLOOD_Lymphoma	OR2AG1 →	+0.027	+3.898	<.001	.005	3	3
LARGE_INTESTINE	ARHGEF10 →	+1.111	+2.628	.006	.002	3	2
LARGE_INTESTINE	NUP88 →	+0.500	+3.321	.001	.003	3	2
LARGE_INTESTINE	TTC19 →	+0.568	+2.628	.004	.002	3	2
LARGE_INTESTINE	CTBS →	+0.857	+3.743	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 512 associations by consensus.

Exploration

NCOA6 survival (RNA) · tumor vs normal (RNA) · all NCOA6 data types