NCOA4P4

Across TCGA patient cohorts, NCOA4P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,785 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NCOA4P4-associated GO terms across cancer lineages are Autophagosome organization, COPII-coated vesicle cargo loading, and Positive regulation of canonical Wnt signaling pathway. Each is linked with NCOA4P4 in more than 23 cancer types. Because this analysis shows association rather than direction, both NCOA4P4-to-partner and partner-to-NCOA4P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome organization grouped by NCOA4P4-low versus NCOA4P4-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA4P4→partner) and Y-score (partner→NCOA4P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Autophagosome organization →	+0.067	+0.075	<.001	.002	3	24
STAD	COPII-coated vesicle cargo loading →	+0.077	+0.154	<.001	<.001	3	23
STAD	Positive regulation of canonical Wnt signaling pathway →	+0.051	+0.139	<.001	<.001	3	23
THYM	Establishment of mitotic sister chromatid cohesion →	+0.073	+0.044	<.001	<.001	3	23
DLBC	Regulation of autophagosome assembly →	+0.074	+0.067	<.001	.001	3	22
ESCA	Positive regulation of autophagosome assembly →	+0.071	+0.161	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,785 associations by consensus.

Autophagosome organization by NCOA4P4 expression — DLBC

Explore this box plot interactively →