Q-omics provides the consensus-scored NCOA4P4 profile across patient tissues and cancer cell-line models. NCOA4P4 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, NCOA4P4 is differentially expressed in 3, with the highest sampling consensus in READ. Additionally, NCOA4P4 RNA expression shows 9,126 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, READ, and THYM as cancer lineages where NCOA4P4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NCOA4P4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NCOA4P4 survival associations across molecular data types. NCOA4P4 RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NCOA4P4 RNA expression–survival associations across cancer types. High NCOA4P4 expression shows unfavorable associations in PAAD, LUAD, CHOL and STAD, but favorable associations in KIRC and HNSC. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for NCOA4P4 RNA expression.
This table summarizes NCOA4P4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in READ for RNA.
This table ranks reproducible tumor–normal expression differences for NCOA4P4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NCOA4P4 shows lower tumor expression in READ, THCA and LUSC. The READ box plot shows higher NCOA4P4 RNA expression in normal versus tumor tissue (log2 FC = −0.065, t-test p = .007).
This table shows molecular features associated with NCOA4P4 in patient tissues and cancer cell lines. In patient samples, NCOA4P4 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
