NCOA4P1

Across TCGA patient cohorts, NCOA4P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,153 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NCOA4P1-associated GO terms across cancer lineages are Vesicle tethering involved in exocytosis, Rescue of stalled ribosome, and Endoplasmic reticulum organization. Each is linked with NCOA4P1 in more than 15 cancer types. Because this analysis shows association rather than direction, both NCOA4P1-to-partner and partner-to-NCOA4P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle tethering involved in exocytosis grouped by NCOA4P1-low versus NCOA4P1-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA4P1→partner) and Y-score (partner→NCOA4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Vesicle tethering involved in exocytosis →	+0.068	+0.269	<.001	<.001	3	15
THYM	Rescue of stalled ribosome →	+0.050	+0.018	<.001	.001	3	15
STAD	Endoplasmic reticulum organization →	+0.043	+0.055	<.001	<.001	3	15
LAML	Synaptic vesicle endosomal processing →	+0.064	+0.245	<.001	<.001	3	14
STAD	Positive regulation of proteasomal protein catabolic process →	+0.047	+0.052	<.001	<.001	3	14
STAD	Positive regulation of proteolysis involved in protein catabolic process →	+0.046	+0.059	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,153 associations by consensus.

Vesicle tethering involved in exocytosis by NCOA4P1 expression — LAML

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