NCOA4P1

Across TCGA pan-cancer cohorts, NCOA4P1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated NCOA4P1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher NCOA4P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NCOA4P1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and BLCA show a favorable association.

STAD, HNSC, and CHOL are the cancer types where NCOA4P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	II,III,IV	0.572	0.720	.006	52	view →
HNSC	OS	Tertile	III,IV	0.445	0.723	.002	30	view →
CHOL	DFS	Tertile	All	0.099	0.501	.015	27	view →
UVM	OS	Tertile	III,IV	0.104	0.813	.001	27	view →
READ	OS	Tertile	IV	0.439	0.824	.005	25	view →
KIRC	DFS	Tertile	III,IV	0.714	0.360	.012	24	view →
BLCA	DFS	Tertile	III,IV	0.750	0.421	.016	24	view →
LIHC	DFS	Tertile	III,IV	1.000	0.284	.016	21	view →
KIRP	DFS	Tertile	All	0.780	0.937	.001	21	view →
KICH	OS	Tertile	II,III,IV	0.155	0.880	<.001	18	view →
ESCA	OS	Median	III,IV	0.683	0.396	.002	15	view →
LAML	DFS	Tertile	All	0.785	0.444	.007	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

NCOA4P1–STAD (OS)

Open the STAD breakdown →