NCOA3

Across TCGA patient cohorts, NCOA3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,103 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible NCOA3-associated proteins across cancer lineages are NCOA3_S728, RPRD1B, and MOCS3. Each is linked with NCOA3 in more than 5 cancer types. Because this analysis shows association rather than direction, both NCOA3-to-partner and partner-to-NCOA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NCOA3 versus NCOA3_S728 in LSCC, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA3→partner) and Y-score (partner→NCOA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NCOA3_S728 →	+0.479	+0.600	<.001	<.001	3	6
GBM	RPRD1B →	+0.348	+0.280	<.001	<.001	3	6
BRCA	MOCS3 →	+0.368	+0.704	<.001	<.001	3	5
COAD	TOP1 →	+0.345	+0.601	<.001	<.001	3	5
LSCC	CSE1L →	+0.339	+0.552	.003	.002	3	4
LUAD	ACSS2_S267 →	+0.406	+0.382	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,103 associations by consensus.

NCOA3 vs NCOA3_S728 — LSCC

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