NCOA3

Across TCGA cell cohorts, NCOA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,946 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NCOA3-associated GO terms across cancer lineages are Vitamin D receptor signaling pathway, Endosomal transport, and Post-Golgi vesicle-mediated transport. Each is linked with NCOA3 in more than 14 cancer types. Because this analysis shows association rather than direction, both NCOA3-to-partner and partner-to-NCOA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vitamin D receptor signaling pathway grouped by NCOA3-low versus NCOA3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA3→partner) and Y-score (partner→NCOA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Vitamin D receptor signaling pathway →	+0.942	+0.643	<.001	.004	3	15
STOMACH	Endosomal transport →	+0.085	+1.513	<.001	.004	3	14
BONE	Post-Golgi vesicle-mediated transport →	+0.097	+0.839	<.001	<.001	3	13
OESOPHAGUS	Dedifferentiation →	+0.250	+1.365	<.001	<.001	3	12
OESOPHAGUS	Cell dedifferentiation →	+0.250	+1.365	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of keratinocyte differentiation →	+0.129	+1.638	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,946 associations by consensus.

Vitamin D receptor signaling pathway by NCOA3 expression — BONE

Explore this box plot interactively →