NCL

Across TCGA patient cohorts, NCL RNA expression is significantly associated with the RNA expression of many other genes, with 19,888 significant associations in total. ACC shows the largest number of these associations.

The most reproducible NCL-associated genes across cancer lineages are MRPL19, WDR75, and CEBPZ. Each is linked with NCL in more than 33 cancer types. Because this analysis shows association rather than direction, both NCL-to-partner and partner-to-NCL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NCL versus MRPL19 in KICH, with a Pearson correlation of 0.80.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCL→partner) and Y-score (partner→NCL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	MRPL19 →	+1.054	+0.875	<.001	<.001	3	34
UVM	WDR75 →	+1.313	+0.887	<.001	<.001	3	34
UVM	CEBPZ →	+1.743	+0.855	<.001	<.001	3	34
KICH	DCAF17 →	+1.031	+0.918	<.001	<.001	3	34
ACC	FARSB →	+1.299	+1.231	<.001	<.001	3	34
DLBC	TTF2 →	+1.105	+0.677	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,888 associations by consensus.

NCL vs MRPL19 — KICH

Explore this scatter interactively →