Across TCGA pan-cancer cohorts, NCKIPSD mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NCKIPSD data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher NCKIPSD mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated NCKIPSD expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, LUAD, and CCRCC are the cancer types where NCKIPSD mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	II,III,IV	0.905	0.575	.008	32	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	11	view →
CCRCC	DFS	Quartile	III,IV	0.687	0.323	.024	5	view →
HNSC	DFS	Median	IV	0.923	0.702	.014	5	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: NCKIPSD tumor-vs-normal RNA expression · all NCKIPSD data types