NCKIPSD

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NCKIPSD mutation is significantly associated with the RNA expression of many other genes, with 402 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCKIPSD-associated genes across cancer lineages are MIR4255, RNU6-1174P, and RPS6P4. Each is linked with NCKIPSD in more than 1 cancer types. Because this analysis shows association rather than direction, both NCKIPSD-to-partner and partner-to-NCKIPSD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCKIPSD→partner) and Y-score (partner→NCKIPSD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADMIR4255 →+0.719+4.859<.001<.00132
STADRNU6-1174P →+0.437+4.855.001<.00132
LUADRPS6P4 →+0.131+5.279<.001.00632
UCECNOP10 →+0.402+2.864.004.00132
UCECCIDECP1 →+0.319+2.556.002.00132
UCECMIRLET7BHG →+0.458+3.721.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 402 associations by consensus.

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