Across TCGA patient cohorts, NCKIPSD mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCKIPSD-associated genes across cancer lineages are ERK2, ATM, and INPP4B. Each is linked with NCKIPSD in more than 1 cancer types. Because this analysis shows association rather than direction, both NCKIPSD-to-partner and partner-to-NCKIPSD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCKIPSD→partner) and Y-score (partner→NCKIPSD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.255	+3.000	.001	.001	3	2
UCEC	ATM →	-0.602	-3.308	.001	.009	3	2
UCEC	INPP4B →	-0.304	-2.321	.023	.034	2	2
UCEC	JNK2 →	+0.310	+2.710	<.001	.003	3	1
UCEC	MSH2 →	-0.269	-1.807	.004	.027	3	1
UCEC	mTOR_pS2448 →	-0.173	-3.308	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

NCKIPSD survival (RNA) · tumor vs normal (RNA) · all NCKIPSD data types