NCKAP5L

Across TCGA pan-cancer cohorts, NCKAP5L mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NCKAP5L data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher NCKAP5L mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NCKAP5L expression acts as an unfavorable survival marker.

PDAC, LUAD, and CCRCC are the cancer types where NCKAP5L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	II,III,IV	0.404	0.663	<.001	58	view →
LUAD	OS	Quartile	All	0.757	0.920	.010	10	view →
CCRCC	DFS	Median	IV	0.188	0.948	.010	9	view →
GBM	OS	Tertile	All	0.344	0.558	.017	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NCKAP5L–PDAC (OS)

Open the PDAC breakdown →