NCKAP5L

Across TCGA patient cohorts, NCKAP5L mutation is significantly associated with the RNA expression of many other genes, with 3,531 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCKAP5L-associated genes across cancer lineages are RAD51, PRC1, and TXNL4A. Each is linked with NCKAP5L in more than 5 cancer types. Because this analysis shows association rather than direction, both NCKAP5L-to-partner and partner-to-NCKAP5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51 grouped by NCKAP5L-low versus NCKAP5L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCKAP5L→partner) and Y-score (partner→NCKAP5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD51 →	+0.673	+1.818	<.001	<.001	3	6
UCEC	PRC1 →	+0.532	+2.008	.002	.001	3	5
SKCM	TXNL4A →	+0.335	+2.926	.003	<.001	3	5
UCEC	GTSE1 →	+0.598	+4.098	<.001	<.001	3	5
UCEC	CENPE →	+0.424	+2.275	.009	.005	3	5
UCEC	SKA1 →	+0.676	+4.108	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,531 associations by consensus.

RAD51 by NCKAP5L expression — UCEC

Explore this box plot interactively →