NCKAP1

Across TCGA patient cohorts, NCKAP1 mutation is significantly associated with the RNA expression of many other genes, with 2,417 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCKAP1-associated genes across cancer lineages are RNU6-89P, UGT1A9, and LINC02342. Each is linked with NCKAP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NCKAP1-to-partner and partner-to-NCKAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-89P grouped by NCKAP1-low versus NCKAP1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCKAP1→partner) and Y-score (partner→NCKAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-89P →	+0.336	+4.315	.002	.007	3	3
SCLC	UGT1A9 →	+0.055	+5.189	.002	.006	3	2
HNSC	LINC02342 →	+0.096	+5.608	<.001	.002	3	2
CESC	OR52X1P →	+0.039	+5.306	<.001	.006	3	2
COAD	RN7SKP44 →	+0.116	+3.212	<.001	.007	3	2
COAD	LINC01789 →	+0.134	+4.734	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,417 associations by consensus.

RNU6-89P by NCKAP1 expression — LUAD

Explore this box plot interactively →