NCKAP1

Across TCGA cell cohorts, NCKAP1 mutation is significantly associated with the RNA expression of many other genes, with 222 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCKAP1-associated genes across cancer lineages are MYH2, TBC1D3H, and C20orf173. Each is linked with NCKAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCKAP1-to-partner and partner-to-NCKAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH2 grouped by NCKAP1-low versus NCKAP1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCKAP1→partner) and Y-score (partner→NCKAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	MYH2 →	+0.019	+4.017	<.001	.007	3	1
LUNG_NSCLC_LUSC	TBC1D3H →	+0.023	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUAD	C20orf173 →	+0.040	+3.977	<.001	.005	3	1
LUNG_NSCLC_LUAD	CLRN1 →	+0.020	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	OR1L6 →	+0.011	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	TARM1 →	+0.019	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 222 associations by consensus.

MYH2 by NCKAP1 expression — OESOPHAGUS

Explore this box plot interactively →