NCF2

Across TCGA patient cohorts, NCF2 mutation is significantly associated with the RNA expression of many other genes, with 1,051 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCF2-associated genes across cancer lineages are RNU6-918P, CIDECP1, and IGHD4-17. Each is linked with NCF2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NCF2-to-partner and partner-to-NCF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-918P grouped by NCF2-low versus NCF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCF2→partner) and Y-score (partner→NCF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-918P →	+0.221	+2.420	.002	.009	3	3
SKCM	CIDECP1 →	+0.373	+1.854	<.001	.005	3	2
SKCM	IGHD4-17 →	+1.099	+1.988	<.001	.001	3	2
UCEC	KRTAP23-1 →	+0.181	+2.132	.002	.009	3	2
UCEC	IGHD1-1 →	+0.333	+2.833	<.001	.009	3	2
COAD	LINC02287 →	+0.125	+3.951	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,051 associations by consensus.

RNU6-918P by NCF2 expression — UCEC

Explore this box plot interactively →