NCBP2L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NCBP2L mutation is significantly associated with the RNA expression of many other genes, with 405 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCBP2L-associated genes across cancer lineages are RNA5SP363, MRPS21P8, and RNU6-1137P. Each is linked with NCBP2L in more than 1 cancer types. Because this analysis shows association rather than direction, both NCBP2L-to-partner and partner-to-NCBP2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP363 grouped by NCBP2L-low versus NCBP2L-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCBP2L→partner) and Y-score (partner→NCBP2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNA5SP363 →+0.609+5.505<.001.00432
HNSCMRPS21P8 →+0.360+5.182<.001.00732
SKCMRNU6-1137P →+0.343+4.680<.001.00732
HNSCRNA5SP448 →+0.347+6.111<.001.00231
HNSCTRAJ54 →+0.550+5.578<.001.00431
HNSCRN7SKP177 →+0.116+5.069.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 405 associations by consensus.

RNA5SP363 by NCBP2L expression — HNSC

Box plot of RNA5SP363 in NCBP2L-low vs NCBP2L-high samples in HNSC.

Explore this box plot interactively →

Exploration