NCBP2L

Across TCGA pan-cancer cohorts, NCBP2L RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of NCBP2L’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where NCBP2L RNA is repressed in tumor relative to normal tissue. In most cancer types NCBP2L is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.

LUSC, KICH, and BRCA are the cancer types where NCBP2L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NCBP2L RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	−0.402	<.001	9	view →
KICH	Female	All	−0.191	<.001	8	view →
BRCA	All	II,III,IV	+0.337	<.001	6	view →
LUAD	All	All	−0.290	<.001	6	view →
PRAD	All	All	+0.272	.001	2	view →
UCEC	All	All	−0.237	.046	2	view →
CHOL	Female	All	−0.170	.024	2	view →
THCA	Female	All	−0.132	.005	2	view →
READ	All	All	−0.058	.021	2	view →
BLCA	Male	IV	−0.205	.003	1	view →
ESCA	All	All	−0.185	.015	1	view →
LIHC	All	All	+0.085	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

NCBP2L–LUSC

Open the LUSC breakdown →