NCBP2AS2

Across TCGA pan-cancer cohorts, NCBP2AS2 mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NCBP2AS2’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where NCBP2AS2 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types NCBP2AS2 is over-expressed in tumor.

LSCC, HNSC, and LUAD are the cancer types where NCBP2AS2 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NCBP2AS2 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	Male	III,IV	+1.172	<.001	8	view →
HNSC	Male	IV	+0.706	<.001	8	view →
LUAD	All	II,III,IV	+0.651	<.001	8	view →
PDAC	Male	All	+0.678	.001	4	view →
CCRCC	Male	III,IV	+0.204	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

NCBP2AS2–LSCC

Open the LSCC breakdown →