NCBP1

Across TCGA pan-cancer cohorts, NCBP1 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated NCBP1 data layer compared with 26 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NCBP1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NCBP1 expression acts as an unfavorable survival marker.

HNSC, SKCM, and ESCA are the cancer types where NCBP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.198	0.756	.002	27	view →
SKCM	OS	Median	II,III,IV	0.291	0.736	.003	18	view →
ESCA	OS	Median	All	0.198	0.872	.003	12	view →
COAD	OS	Median	All	0.175	0.809	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →
LUAD	OS	Median	All	0.241	0.684	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

NCBP1–HNSC (OS)

Open the HNSC breakdown →