NCBP1

Across TCGA pan-cancer cohorts, NCBP1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of NCBP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NCBP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NCBP1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

HNSC, BLCA, and THCA are the cancer types where NCBP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NCBP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+0.996	<.001	11	view →
BLCA	All	III,IV	+0.652	<.001	10	view →
THCA	Male	II,III,IV	−0.616	<.001	9	view →
STAD	Male	II,III,IV	+1.128	<.001	8	view →
LUSC	Female	All	+1.115	<.001	8	view →
COAD	Male	IV	+0.680	<.001	7	view →
LUAD	Male	All	+0.640	<.001	7	view →
LIHC	All	All	+0.432	<.001	7	view →
READ	All	II,III,IV	+0.559	.013	6	view →
BRCA	All	III,IV	+0.538	<.001	6	view →
KIRC	All	II,III,IV	−0.335	.002	5	view →
CHOL	All	All	+1.251	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

NCBP1–HNSC

Open the HNSC breakdown →