NCBP1

Across TCGA patient cohorts, NCBP1 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCBP1-associated genes across cancer lineages are Caspase-7-cleavedD198, PDCD4, and ATM. Each is linked with NCBP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NCBP1-to-partner and partner-to-NCBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by NCBP1-low versus NCBP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCBP1→partner) and Y-score (partner→NCBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.363	+1.460	.038	.013	3	3
UCEC	PDCD4 →	-0.385	-1.999	.005	.008	3	2
UCEC	ATM →	-0.334	-1.241	.012	.015	3	2
UCEC	cIAP →	+0.091	+1.935	.023	.002	3	2
UCEC	14-3-3_beta →	-0.085	-2.475	.004	.001	3	1
UCEC	eIF4E →	+0.158	+2.392	.011	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Caspase-7-cleavedD198 by NCBP1 expression — UCEC

Explore this box plot interactively →