NCAPH2

Across TCGA patient cohorts, NCAPH2 mutation is significantly associated with the RNA expression of many other genes, with 1,337 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCAPH2-associated genes across cancer lineages are CXCL13, TUBGCP5, and LINC00869. Each is linked with NCAPH2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NCAPH2-to-partner and partner-to-NCAPH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CXCL13 grouped by NCAPH2-low versus NCAPH2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPH2→partner) and Y-score (partner→NCAPH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CXCL13 →	+1.846	+3.807	<.001	<.001	3	3
UCEC	TUBGCP5 →	+0.441	+2.447	.002	.001	3	2
UCEC	LINC00869 →	-0.596	-3.023	<.001	<.001	3	2
UCEC	TIGIT →	+0.885	+3.087	<.001	<.001	3	2
UCEC	GINS3 →	+0.582	+3.617	<.001	.001	3	2
UCEC	SMYD4 →	+0.526	+2.457	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,337 associations by consensus.

CXCL13 by NCAPH2 expression — UCEC

Explore this box plot interactively →