NCAPH2

Across TCGA pan-cancer cohorts, NCAPH2 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated NCAPH2 data layer compared with 2 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher NCAPH2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NCAPH2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.

ACC, LIHC, and KICH are the cancer types where NCAPH2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.140	0.715	<.001	105	view →
LIHC	DFS	Median	All	0.464	0.619	<.001	99	view →
KICH	OS	Tertile	II,III,IV	0.592	1.000	.001	76	view →
HNSC	OS	Tertile	II,III,IV	0.818	0.675	.004	55	view →
CESC	OS	Median	All	0.719	0.433	<.001	36	view →
MESO	OS	Median	All	0.274	0.503	<.001	26	view →
PRAD	DFS	Median	All	0.685	0.890	<.001	24	view →
READ	DFS	Median	All	0.791	0.621	.015	23	view →
THYM	OS	Tertile	All	0.943	0.673	.012	21	view →
GBM	DFS	Tertile	All	0.377	0.175	.008	18	view →
LAML	DFS	Quartile	All	0.307	0.618	.020	18	view →
KIRC	DFS	Tertile	All	0.850	0.729	.009	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

NCAPH2–ACC (DFS)

Open the ACC breakdown →