NCAPH2

Across TCGA patient cohorts, NCAPH2 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCAPH2-associated genes across cancer lineages are PDCD4, Caspase-7-cleavedD198, and eEF2. Each is linked with NCAPH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCAPH2-to-partner and partner-to-NCAPH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by NCAPH2-low versus NCAPH2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPH2→partner) and Y-score (partner→NCAPH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.567	-3.459	.004	.005	3	2
UCEC	Caspase-7-cleavedD198 →	+1.000	+2.827	<.001	.001	3	2
UCEC	eEF2 →	+0.330	+2.222	.029	.011	3	1
UCEC	ERK2 →	+0.196	+3.169	.016	.018	3	1
UCEC	JNK2 →	+0.279	+2.222	<.001	.011	3	1
UCEC	Ku80 →	+0.278	+2.235	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

PDCD4 by NCAPH2 expression — UCEC

Explore this box plot interactively →