NCAPH2

Across TCGA cell cohorts, NCAPH2 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NCAPH2-associated genes across cancer lineages are FAM205A, HAO2, and ADRA1A. Each is linked with NCAPH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCAPH2-to-partner and partner-to-NCAPH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM205A grouped by NCAPH2-low versus NCAPH2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPH2→partner) and Y-score (partner→NCAPH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM205A →	+0.025	+4.614	<.001	.002	3	1
BLOOD_Leukemia	HAO2 →	+0.033	+3.234	.002	.008	3	1
BLOOD_Leukemia	ADRA1A →	+0.154	+4.121	<.001	<.001	3	1
BLOOD_Leukemia	C20orf85 →	+0.015	+3.969	.005	.009	3	1
BLOOD_Leukemia	TTC29 →	+0.161	+3.623	<.001	.007	3	1
BLOOD_Leukemia	FRZB →	+0.531	+3.847	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

FAM205A by NCAPH2 expression — LARGE_INTESTINE

Explore this box plot interactively →