NCAPH

Across TCGA cell cohorts, NCAPH mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible NCAPH-associated genes across cancer lineages are OR1D4, KRTAP5-4, and MMP26. Each is linked with NCAPH in more than 1 cancer types. Because this analysis shows association rather than direction, both NCAPH-to-partner and partner-to-NCAPH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1D4 grouped by NCAPH-low versus NCAPH-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPH→partner) and Y-score (partner→NCAPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR1D4 →	+0.046	+4.539	<.001	.007	3	2
SKIN	KRTAP5-4 →	+0.101	+4.977	<.001	.007	3	1
STOMACH	MMP26 →	+0.673	+5.285	<.001	.003	3	1
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR5V1 →	+0.005	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

OR1D4 by NCAPH expression — BLOOD_Leukemia

Explore this box plot interactively →