NCAPG

Across TCGA patient cohorts, NCAPG mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCAPG-associated genes across cancer lineages are ERK2, GAPDH, and MEK1. Each is linked with NCAPG in more than 2 cancer types. Because this analysis shows association rather than direction, both NCAPG-to-partner and partner-to-NCAPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by NCAPG-low versus NCAPG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPG→partner) and Y-score (partner→NCAPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.169	+1.584	.003	.002	3	3
UCEC	GAPDH →	+0.349	+1.807	.029	.024	3	2
UCEC	MEK1 →	+0.451	+2.050	<.001	<.001	3	2
UCEC	mTOR_pS2448 →	-0.114	-1.717	.010	.006	3	2
UCEC	Notch1 →	+0.148	+1.450	<.001	.014	3	2
UCEC	p62 Lck ligand →	+0.373	+3.169	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

ERK2 by NCAPG expression — UCEC

Explore this box plot interactively →