NCAPG

Across TCGA pan-cancer cohorts, NCAPG RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated NCAPG data layer compared with 4 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher NCAPG RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NCAPG expression acts as an unfavorable survival marker, although some lineages such as READ and THYM show a favorable association.

KIRP, MESO, and ACC are the cancer types where NCAPG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.844	0.968	<.001	155	view →
MESO	OS	Median	All	0.366	0.718	<.001	150	view →
ACC	OS	Median	All	0.378	0.825	<.001	137	view →
LIHC	DFS	Median	All	0.455	0.625	<.001	100	view →
KICH	DFS	Tertile	III,IV	0.142	1.000	<.001	95	view →
KIRC	DFS	Quartile	All	0.459	0.698	<.001	91	view →
UVM	DFS	Quartile	All	0.264	0.846	<.001	88	view →
LUAD	OS	Median	All	0.617	0.750	<.001	80	view →
LGG	OS	Median	All	0.715	0.909	<.001	54	view →
PAAD	OS	Tertile	All	0.257	0.555	<.001	50	view →
READ	DFS	Quartile	II,III,IV	0.784	0.263	.003	44	view →
SARC	DFS	Tertile	All	0.508	0.701	<.001	33	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

NCAPG–KIRP (DFS)

Open the KIRP breakdown →