NCAPD3

Across TCGA cell cohorts, NCAPD3 mutation is significantly associated with the RNA expression of many other genes, with 597 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCAPD3-associated genes across cancer lineages are LRRC72, USP42, and MAPK8. Each is linked with NCAPD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCAPD3-to-partner and partner-to-NCAPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRRC72 grouped by NCAPD3-low versus NCAPD3-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAPD3→partner) and Y-score (partner→NCAPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	LRRC72 →	+0.019	+5.000	<.001	.006	3	2
LARGE_INTESTINE	USP42 →	+0.382	+2.129	.009	.007	3	2
LARGE_INTESTINE	MAPK8 →	+0.649	+3.169	.002	.006	3	2
LARGE_INTESTINE	ATP5F1B →	+0.549	+2.043	<.001	.008	3	2
LARGE_INTESTINE	NOP2 →	+0.598	+2.043	.001	.008	3	2
LARGE_INTESTINE	SUDS3 →	+0.425	+3.596	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 597 associations by consensus.

LRRC72 by NCAPD3 expression — PANCREAS

Explore this box plot interactively →