NCAM1

Across TCGA cell cohorts, NCAM1 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCAM1-associated genes across cancer lineages are ARL6, TMX1, and WRAP53. Each is linked with NCAM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCAM1-to-partner and partner-to-NCAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARL6 grouped by NCAM1-low versus NCAM1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCAM1→partner) and Y-score (partner→NCAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ARL6 →	+0.455	+3.252	.001	.002	3	2
LARGE_INTESTINE	TMX1 →	+0.505	+2.949	.002	<.001	3	2
LARGE_INTESTINE	WRAP53 →	+0.526	+2.584	.001	.002	3	2
LARGE_INTESTINE	BICD1 →	+0.720	+2.265	.005	.001	3	2
LARGE_INTESTINE	RABEP1 →	+0.514	+2.351	.006	.001	3	2
BLOOD_Leukemia	PROP1 →	+0.018	+3.289	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

ARL6 by NCAM1 expression — LARGE_INTESTINE

Explore this box plot interactively →