NCALD

Across TCGA pan-cancer cohorts, NCALD Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NCALD data layer compared with 24 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NCALD Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NCALD expression acts as an unfavorable survival marker.

LUAD, COAD, and MESO are the cancer types where NCALD Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.057	0.709	<.001	24	view →
COAD	OS	Median	II,III,IV	0.111	0.853	<.001	12	view →
MESO	DFS	Median	III,IV	0.078	0.376	.012	9	view →
CESC	OS	Median	All	0.277	0.798	.012	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NCALD–LUAD (OS)

Open the LUAD breakdown →