NCALD

Across TCGA patient cohorts, NCALD protein abundance is significantly associated with the RNA expression of many other genes, with 12,987 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NCALD-associated genes across cancer lineages are GREM2, CLEC4F, and SCUBE2. Each is linked with NCALD in more than 4 cancer types. Because this analysis shows association rather than direction, both NCALD-to-partner and partner-to-NCALD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NCALD versus GREM2 in UCEC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCALD→partner) and Y-score (partner→NCALD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GREM2 →	+1.759	+0.549	<.001	.001	3	5
BRCA	CLEC4F →	+0.906	+0.400	<.001	.007	3	5
UCEC	SCUBE2 →	+1.059	+0.661	<.001	<.001	3	4
LUAD	RGS7BP →	+1.007	+0.572	<.001	<.001	3	4
BRCA	RRM2B →	+0.802	+0.542	<.001	.002	3	4
UCEC	FBLN1 →	+1.246	+0.559	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,987 associations by consensus.

NCALD vs GREM2 — UCEC

Explore this scatter interactively →