Across TCGA patient cohorts, NBR1 mutation is significantly associated with the RNA expression of many other genes, with 3,009 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBR1-associated genes across cancer lineages are RNU6-1252P, NCAPG, and AQP7P2. Each is linked with NBR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NBR1-to-partner and partner-to-NBR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBR1→partner) and Y-score (partner→NBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1252P →	+0.121	+5.832	<.001	<.001	3	3
UCEC	NCAPG →	+0.557	+2.815	.007	.001	3	3
UCEC	AQP7P2 →	+0.107	+1.595	<.001	.005	3	3
SKCM	SLC29A4P2 →	+0.012	+2.993	.002	.008	3	3
SKCM	STARD4 →	+1.142	+3.340	.001	.005	3	3
GBM	RN7SL383P →	+0.219	+5.352	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,009 associations by consensus.

Exploration

NBR1 survival (RNA) · tumor vs normal (RNA) · all NBR1 data types