Across TCGA patient cohorts, NBPF6 mutation is significantly associated with the RNA expression of many other genes, with 727 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF6-associated genes across cancer lineages are RNU6-1106P, RNU6-351P, and PTPRJ. Each is linked with NBPF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF6-to-partner and partner-to-NBPF6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF6→partner) and Y-score (partner→NBPF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1106P →	+0.271	+7.741	<.001	.009	3	1
COAD	RNU6-351P →	+0.284	+7.741	<.001	.009	3	1
UCEC	PTPRJ →	+0.791	+3.332	.006	.005	3	1
UCEC	MTA2 →	+0.650	+3.386	<.001	.004	3	1
UCEC	CHEK1 →	+0.911	+3.343	.001	.005	3	1
UCEC	TIRAP →	+0.613	+3.354	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 727 associations by consensus.

Exploration

NBPF6 survival (RNA) · tumor vs normal (RNA) · all NBPF6 data types