NBPF25P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NBPF25P mutation is significantly associated with the RNA expression of many other genes, with 452 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF25P-associated genes across cancer lineages are SNORD116-23, LINC01066, and GPR32. Each is linked with NBPF25P in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF25P-to-partner and partner-to-NBPF25P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD116-23 grouped by NBPF25P-low versus NBPF25P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF25P→partner) and Y-score (partner→NBPF25P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSNORD116-23 →+0.619+2.847.001<.00132
SKCMLINC01066 →+0.120+2.815<.001.00632
COADGPR32 →+0.077+5.145<.001.00732
SKCMMIR4444-2 →+0.267+2.622.007.00532
LUADOR6C76 →+0.061+4.798<.001.00632
LUADMIR4450 →+0.840+4.598<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 452 associations by consensus.

SNORD116-23 by NBPF25P expression — UCEC

Box plot of SNORD116-23 in NBPF25P-low vs NBPF25P-high samples in UCEC.

Explore this box plot interactively →

Exploration