NBPF25P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NBPF25P RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated NBPF25P data layer compared with 4 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher NBPF25P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NBPF25P expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

ACC, HNSC, and BRCA are the cancer types where NBPF25P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCDFSMedianAll0.2540.643<.001102view →
HNSCOSTertileAll0.8360.688<.00161view →
BRCAOSTertileAll0.9780.941.00250view →
MESODFSTertileAll0.2680.439.00249view →
LGGDFSMedianAll0.6630.813<.00145view →
PAADOSMedianAll0.5020.302.00836view →
CESCDFSQuartileIII,IV0.1000.852.00236view →
READOSTertileII,III,IV0.9800.837.00831view →
ESCADFSMedianIV0.2050.634.00630view →
KIRCDFSQuartileAll0.9150.844.00723view →
KICHOSMedianAll0.7390.974.00320view →
LIHCOSTertileII,III,IV0.4570.695.00220view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

NBPF25P–ACC (DFS)

Kaplan–Meier survival curve for NBPF25P RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration