NBPF25P

Across TCGA patient cohorts, NBPF25P mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF25P-associated genes across cancer lineages are MEK1, JNK_pT183_Y185, and Ku80. Each is linked with NBPF25P in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF25P-to-partner and partner-to-NBPF25P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by NBPF25P-low versus NBPF25P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF25P→partner) and Y-score (partner→NBPF25P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.503	+3.169	.012	.020	3	2
UCEC	JNK_pT183_Y185 →	-0.221	-3.156	.016	.020	3	1
UCEC	Ku80 →	+0.305	+3.183	.018	.010	3	1
UCEC	p62 Lck ligand →	+0.523	+3.169	.003	.020	2	1
UCEC	C-Raf →	+0.200	+3.169	.011	.020	2	1
UCEC	Cyclin-B1 →	+0.644	+3.169	.036	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MEK1 by NBPF25P expression — UCEC

Explore this box plot interactively →