NBPF20

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NBPF20 mutation is significantly associated with the RNA expression of many other genes, with 55 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NBPF20-associated genes across cancer lineages are TIFAB, PRR30, and LMX1A. Each is linked with NBPF20 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF20-to-partner and partner-to-NBPF20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIFAB grouped by NBPF20-low versus NBPF20-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF20→partner) and Y-score (partner→NBPF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaTIFAB →+0.124+2.807.008.00532
LUNG_NSCLC_LUADPRR30 →+0.006+3.189.006.00732
PANCREASLMX1A →+0.224+4.786<.001.00131
PANCREASSPAG11B →+0.107+4.614<.001.00431
PANCREASKRTAP10-12 →+0.020+4.614<.001.00431
PANCREASIQCF3 →+0.113+4.491<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

TIFAB by NBPF20 expression — BLOOD_Lymphoma

Box plot of TIFAB in NBPF20-low vs NBPF20-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration